Fast, Non-Competitive and Reversible Inhibition of NMDA-Activated Currents by 2-BFI Confers Neuroprotection

Excessive activation of the N-methyl-D-aspartic acid (NMDA) type glutamate receptors (NMDARs) causes excitotoxicity, a process important in stroke-induced neuronal death. Drugs that inhibit NMDA receptor-mediated [Ca(2+)]i influx are potential leads for development to treat excitotoxicity-induced br...

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Detalles Bibliográficos
Autores principales: Han, Zhao, Yang, Jin-Long, Jiang, Susan X., Hou, Sheng-Tao, Zheng, Rong-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669129/
https://www.ncbi.nlm.nih.gov/pubmed/23741413
http://dx.doi.org/10.1371/journal.pone.0064894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669129/
https://www.ncbi.nlm.nih.gov/pubmed/23741413
http://dx.doi.org/10.1371/journal.pone.0064894

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