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ApoE4 Induces Synaptic and ERG Impairments in the Retina of Young Targeted Replacement ApoE4 Mice

The vertebrate retina, which is part of the central nervous system, is a window into the brain. The present study investigated the extent to which the retina can be used as a model for studying the pathological effects of apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for Alzheime...

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Detalles Bibliográficos
Autores principales: Antes, Ran, Ezra-Elia, Raaya, Weinberger, Dov, Solomon, Arie, Ofri, Ron, Michaelson, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669199/
https://www.ncbi.nlm.nih.gov/pubmed/23741431
http://dx.doi.org/10.1371/journal.pone.0064949