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Robust Automated Detection of Microstructural White Matter Degeneration in Alzheimer’s Disease Using Machine Learning Classification of Multicenter DTI Data

Diffusion tensor imaging (DTI) based assessment of white matter fiber tract integrity can support the diagnosis of Alzheimer’s disease (AD). The use of DTI as a biomarker, however, depends on its applicability in a multicenter setting accounting for effects of different MRI scanners. We applied mult...

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Detalles Bibliográficos
Autores principales: Dyrba, Martin, Ewers, Michael, Wegrzyn, Martin, Kilimann, Ingo, Plant, Claudia, Oswald, Annahita, Meindl, Thomas, Pievani, Michela, Bokde, Arun L. W., Fellgiebel, Andreas, Filippi, Massimo, Hampel, Harald, Klöppel, Stefan, Hauenstein, Karlheinz, Kirste, Thomas, Teipel, Stefan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669206/
https://www.ncbi.nlm.nih.gov/pubmed/23741425
http://dx.doi.org/10.1371/journal.pone.0064925