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Sorafenib Inhibits Epithelial-Mesenchymal Transition through an Epigenetic-Based Mechanism in Human Lung Epithelial Cells

The epithelial to mesenchymal transition (EMT) has been well recognized for many decades as an essential early step in the progression of primary tumors towards metastases. Widespread epigenetic reprogramming of DNA and histone modifications tightly regulates gene expression and cellular activity du...

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Detalles Bibliográficos
Autores principales: Zhang, Juyong, Chen, Yue-Lei, Ji, Guanyu, Fang, Weiying, Gao, Zhaowei, Liu, Yi, Wang, Jun, Ding, Xiaoyan, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669213/
https://www.ncbi.nlm.nih.gov/pubmed/23741434
http://dx.doi.org/10.1371/journal.pone.0064954