Cargando…

Sorafenib Inhibits Epithelial-Mesenchymal Transition through an Epigenetic-Based Mechanism in Human Lung Epithelial Cells

The epithelial to mesenchymal transition (EMT) has been well recognized for many decades as an essential early step in the progression of primary tumors towards metastases. Widespread epigenetic reprogramming of DNA and histone modifications tightly regulates gene expression and cellular activity du...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Juyong, Chen, Yue-Lei, Ji, Guanyu, Fang, Weiying, Gao, Zhaowei, Liu, Yi, Wang, Jun, Ding, Xiaoyan, Gao, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669213/ https://www.ncbi.nlm.nih.gov/pubmed/23741434 http://dx.doi.org/10.1371/journal.pone.0064954

Ejemplares similares

Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
por: Deng, Yan-Ru, et al.
Publicado: (2016)

Regorafenib reverses HGF‐induced sorafenib resistance by inhibiting epithelial‐mesenchymal transition in hepatocellular carcinoma
por: Chen, Weibo, et al.
Publicado: (2019)

Epigenetic reprogramming in the epithelial-to-mesenchymal transition
por: Hoang, Stephen, et al.
Publicado: (2012)

Epigenetic Regulation of the Epithelial to Mesenchymal Transition in Lung Cancer
por: Roche, Joëlle, et al.
Publicado: (2017)

Sorafenib suppresses the epithelial-mesenchymal transition of hepatocellular carcinoma cells after insufficient radiofrequency ablation
por: Dong, Shuying, et al.
Publicado: (2015)

Sorafenib Ameliorates Renal Fibrosis through Inhibition of TGF-β-Induced Epithelial-Mesenchymal Transition
por: Jia, Lining, et al.
Publicado: (2015)

Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial–mesenchymal transition and fibroblast activation
por: Chen, Y-L, et al.
Publicado: (2013)

Corrigendum to: Regorafenib reverses HGF‐induced sorafenib resistance by inhibiting epithelial‐mesenchymal transition in hepatocellular carcinoma
Publicado: (2022)

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
por: Sciacovelli, Marco, et al.
Publicado: (2016)

Tackle Epithelial-Mesenchymal Transition With Epigenetic Drugs in Cancer
por: Dong, Bo, et al.
Publicado: (2020)

Genome-scale epigenetic reprogramming during epithelial to mesenchymal transition
por: McDonald, Oliver G., et al.
Publicado: (2011)

Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition
por: Cieślik, Marcin, et al.
Publicado: (2013)

Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes
por: Kao, Shih-Han, et al.
Publicado: (2016)

Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis
por: Chen, Hsiao-Fan, et al.
Publicado: (2016)

Epigenetic Mechanisms Influencing Epithelial to Mesenchymal Transition in Bladder Cancer
por: Monteiro-Reis, Sara, et al.
Publicado: (2019)

A 17 gene panel for non‐small‐cell lung cancer prognosis identified through integrative epigenomic‐transcriptomic analyses of hypoxia‐induced epithelial–mesenchymal transition
por: Chen, Yue‐Lei, et al.
Publicado: (2019)

Sorafenib inhibits ovarian cancer cell proliferation and mobility and induces radiosensitivity by targeting the tumor cell epithelial–mesenchymal transition
por: Tian, Chuntao, et al.
Publicado: (2022)

Ionizing radiation induces epithelial–mesenchymal transition in human bronchial epithelial cells
por: Tang, Bo, et al.
Publicado: (2020)

PDCD2 sensitizes HepG2 cells to sorafenib by suppressing epithelial-mesenchymal transition
por: Liu, Hongyu, et al.
Publicado: (2019)

Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer
por: Lee, Jaewang, et al.
Publicado: (2020)

KPNA3 Confers Sorafenib Resistance to Advanced Hepatocellular Carcinoma via TWIST Regulated Epithelial-Mesenchymal Transition
por: Hu, Bo, et al.
Publicado: (2019)

Trichostatin A inhibits radiation-induced epithelial-to-mesenchymal transition in the alveolar epithelial cells
por: Nagarajan, Devipriya, et al.
Publicado: (2017)

Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions
por: Guo, Fei, et al.
Publicado: (2014)

Lipoxin A(4) ameliorates lipopolysaccharide-induced lung injury through stimulating epithelial proliferation, reducing epithelial cell apoptosis and inhibits epithelial–mesenchymal transition
por: Yang, Jing-xiang, et al.
Publicado: (2019)

Cortactin in Epithelial–Mesenchymal Transition
por: Ji, Rong, et al.
Publicado: (2020)

Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer
por: Chen, Yang, et al.
Publicado: (2016)

Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells
por: Xu, Gui-Li, et al.
Publicado: (2020)

Lung cancer exosomes as drivers of epithelial mesenchymal transition
por: Rahman, Mohammad A., et al.
Publicado: (2016)

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
por: Malouf, Gabriel G, et al.
Publicado: (2013)

Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer
por: Bedi, Upasana, et al.
Publicado: (2014)

Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
por: Serrano-Gomez, Silvia Juliana, et al.
Publicado: (2016)

Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis
por: Skibba, Melissa, et al.
Publicado: (2020)

LncRNAs as epigenetic regulators of epithelial to mesenchymal transition in pancreatic cancer
por: Ma, Yan, et al.
Publicado: (2022)

Hydrogen sulfide inhibits epithelial-mesenchymal transition in peritoneal mesothelial cells
por: Cheng, Shengnan, et al.
Publicado: (2018)

Metadherin regulates epithelial–mesenchymal transition in carcinoma
por: Wang, Zhao, et al.
Publicado: (2016)

Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells
por: Takano, Chika, et al.
Publicado: (2022)

C-phycocyanin inhibits epithelial-to-mesenchymal transition in Caski cells
por: Ji, Huanhuan, et al.
Publicado: (2020)

Correction: Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer
por: Chen, Yang, et al.
Publicado: (2018)

Progesterone Inhibits Epithelial-to-Mesenchymal Transition in Endometrial Cancer
por: van der Horst, Paul H., et al.
Publicado: (2012)

Epigenetic Regulation of Elf5 Is Associated with Epithelial-Mesenchymal Transition in Urothelial Cancer
por: Wu, Bo, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rml8p7ohs15n2jcafh1lievv30