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Altered Composition of Bone as Triggered by Irradiation Facilitates the Rapid Erosion of the Matrix by Both Cellular and Physicochemical Processes

Radiation rapidly undermines trabecular architecture, a destructive process which proceeds despite a devastated cell population. In addition to the ‘biologically orchestrated’ resorption of the matrix by osteoclasts, physicochemical processes enabled by a damaged matrix may contribute to the rapid e...

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Detalles Bibliográficos
Autores principales: Green, Danielle E., Adler, Benjamin J., Chan, Meilin Ete, Lennon, James J., Acerbo, Alvin S., Miller, Lisa M., Rubin, Clinton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669258/
https://www.ncbi.nlm.nih.gov/pubmed/23741433
http://dx.doi.org/10.1371/journal.pone.0064952