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Stronger T Cell Immunogenicity of Ovalbumin Expressed Intracellularly in Gram-Negative than in Gram-Positive Bacteria

This study aimed to clarify whether Gram-positive (G+) and Gram-negative (G−) bacteria affect antigen-presenting cells differently and thereby influence the immunogenicity of proteins they express. Lactobacilli, lactococci and Escherichia coli strains were transformed with plasmids conferring intrac...

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Detalles Bibliográficos
Autores principales: Martner, Anna, Östman, Sofia, Lundin, Samuel, Rask, Carola, Björnsson, Viktor, Telemo, Esbjörn, Collins, L. Vincent, Axelsson, Lars, Wold, Agnes E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669294/
https://www.ncbi.nlm.nih.gov/pubmed/23741469
http://dx.doi.org/10.1371/journal.pone.0065124