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Circulating Mitochondrial DNA as Biomarker Linking Environmental Chemical Exposure to Early Preclinical Lesions Elevation of mtDNA in Human Serum after Exposure to Carcinogenic Halo-Alkane-Based Pesticides

There is a need for a panel of suitable biomarkers for detection of environmental chemical exposure leading to the initiation or progression of degenerative diseases or potentially, to cancer. As the peripheral blood may contain increased levels of circulating cell-free DNA in diseased individuals,...

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Detalles Bibliográficos
Autores principales: Budnik, Lygia T., Kloth, Stefan, Baur, Xaver, Preisser, Alexandra M., Schwarzenbach, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669318/
https://www.ncbi.nlm.nih.gov/pubmed/23741329
http://dx.doi.org/10.1371/journal.pone.0064413