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Branched Motifs Enable Long-Range Interactions in Signaling Networks through Retrograde Propagation

Branched structures arise in the intra-cellular signaling network when a molecule is involved in multiple enzyme-substrate reaction cascades. Such branched motifs are involved in key biological processes, e.g., immune response activated by T-cell and B-cell receptors. In this paper, we demonstrate l...

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Detalles Bibliográficos
Autores principales: Jesan, Tharmaraj, Sarma, Uddipan, Halder, Subhadra, Saha, Bhaskar, Sinha, Sitabhra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669326/
https://www.ncbi.nlm.nih.gov/pubmed/23741327
http://dx.doi.org/10.1371/journal.pone.0064409