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Cadmium-Induced Apoptosis in Primary Rat Cerebral Cortical Neurons Culture Is Mediated by a Calcium Signaling Pathway
Cadmium (Cd) is an extremely toxic metal, capable of severely damaging several organs, including the brain. Studies have shown that Cd disrupts intracellular free calcium ([Ca(2+)](i)) homeostasis, leading to apoptosis in a variety of cells including primary murine neurons. Calcium is a ubiquitous i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669330/ https://www.ncbi.nlm.nih.gov/pubmed/23741317 http://dx.doi.org/10.1371/journal.pone.0064330 |