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Hydrogen Sulfide Prevents Hydrogen Peroxide-Induced Activation of Epithelial Sodium Channel through a PTEN/PI(3,4,5)P(3) Dependent Pathway
Sodium reabsorption through the epithelial sodium channel (ENaC) at the distal segment of the kidney plays an important role in salt-sensitive hypertension. We reported previously that hydrogen peroxide (H(2)O(2)) stimulates ENaC in A6 distal nephron cells via elevation of phosphatidylinositol 3,4,5...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669336/ https://www.ncbi.nlm.nih.gov/pubmed/23741314 http://dx.doi.org/10.1371/journal.pone.0064304 |