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Increased Levels of Plasma Soluble Sema4D in Patients with Heart Failure

Semaphorin 4D (Sema4D/CD100) is a 150-kDa transmembrane glycoprotein expressed by platelets and T-cells. When these cells are activated, Sema4D is cleaved proteolytically, generating a biologically active 120-kDa fragment (soluble Sema4D) capable of targeting receptors on platelets, B-cells, endothe...

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Detalles Bibliográficos
Autores principales: Lu, Qiongyu, Dong, Ningzheng, Wang, Qi, Yi, Wenxiu, Wang, Yuxin, Zhang, Shengjie, Gu, Haibo, Zhao, Xin, Tang, Xiaorong, Jin, Boquan, Wu, Qingyu, Brass, Lawrence F., Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669357/
https://www.ncbi.nlm.nih.gov/pubmed/23741311
http://dx.doi.org/10.1371/journal.pone.0064265