Transforming Growth Factor-β1 (TGF-β1) Regulates Cell Junction Restructuring via Smad-Mediated Repression and Clathrin-Mediated Endocytosis of Nectin-like Molecule 2 (Necl-2)

Nectin-like molecule-2 (Necl-2), a junction molecule, is exclusively expressed by spermatogenic cells. It mediates homophilic interaction between germ cells and heterophilic interaction between Sertoli and germ cells. Knockout studies have shown that loss of Necl-2 causes male infertility, suggestin...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Lui, Wing-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669379/
https://www.ncbi.nlm.nih.gov/pubmed/23741316
http://dx.doi.org/10.1371/journal.pone.0064316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669379/
https://www.ncbi.nlm.nih.gov/pubmed/23741316
http://dx.doi.org/10.1371/journal.pone.0064316

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