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Endothelial Nitric Oxide Synthase Reduces Crescentic and Necrotic Glomerular Lesions, Reactive Oxygen Production, and MCP1 Production in Murine Lupus Nephritis

Systemic lupus erythematosus, in both animal models and in humans, is characterized by autoantibody production followed by immune complex deposition in target tissues. Ensuing target organ damage is modulated by reactive intermediates, including reactive nitrogen and oxygen species, through as of no...

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Detalles Bibliográficos
Autores principales: Gilkeson, Gary S., Mashmoushi, Ahmad K., Ruiz, Phillip, Caza, Tiffany N., Perl, Andras, Oates, Jim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669382/
https://www.ncbi.nlm.nih.gov/pubmed/23741359
http://dx.doi.org/10.1371/journal.pone.0064650