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Effects of DNMT1 and HDAC Inhibitors on Gene-Specific Methylation Reprogramming during Porcine Somatic Cell Nuclear Transfer
Somatic cell nuclear transfer (SCNT) in mammalian cloning currently remains inefficient. Incomplete or erroneous epigenetic reprogramming of specialized donor somatic nuclear and resulting aberrant gene expression during development of cloned embryos is commonly believed as the main reason that caus...
Autores principales: | Xu, Weihua, Li, Zicong, Yu, Bo, He, Xiaoyan, Shi, Junsong, Zhou, Rong, Liu, Dewu, Wu, Zhenfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669391/ https://www.ncbi.nlm.nih.gov/pubmed/23741375 http://dx.doi.org/10.1371/journal.pone.0064705 |
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