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Inhibition of UBE2D3 Expression Attenuates Radiosensitivity of MCF-7 Human Breast Cancer Cells by Increasing hTERT Expression and Activity

The known functions of telomerase in tumor cells include replenishing telomeric DNA and maintaining cell immortality. We have previously shown the existence of a negative correlation between human telomerase reverse transcriptase (hTERT) and radiosensitivity in tumor cells. Here we set out to elucid...

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Detalles Bibliográficos
Autores principales: Wang, Wenbo, Yang, Lei, Hu, Liu, Li, Fen, Ren, Li, Yu, Haijun, Liu, Yu, Xia, Ling, Lei, Han, Liao, Zhengkai, Zhou, Fuxiang, Xie, Conghua, Zhou, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669415/
https://www.ncbi.nlm.nih.gov/pubmed/23741361
http://dx.doi.org/10.1371/journal.pone.0064660