Cargando…

Does Naloxone Reinstate Secondary Hyperalgesia in Humans after Resolution of a Burn Injury? A Placebo-Controlled, Double-Blind, Randomized, Cross-Over Study

INTRODUCTION: Development of secondary hyperalgesia following a cutaneous injury is a centrally mediated, robust phenomenon. The pathophysiological role of endogenous opioid signalling to the development of hyperalgesia is unclear. Recent animal studies, carried out after the resolution of inflammat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pereira, Manuel P., Werner, Mads U., Ringsted, Thomas K., Rowbotham, Michael C., Taylor, Bradley K., Dahl, Joergen B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669421/ https://www.ncbi.nlm.nih.gov/pubmed/23741350 http://dx.doi.org/10.1371/journal.pone.0064608

Ejemplares similares

Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial
por: Pereira, Manuel Pedro, et al.
Publicado: (2015)

Erratum to: ‘Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial’
por: Pereira, Manuel Pedro, et al.
Publicado: (2016)

Effects of target-controlled infusion of high-dose naloxone on pain and hyperalgesia in a human thermal injury model: a study protocol: A randomized, double-blind, placebo-controlled, crossover trial with an enriched design
por: Springborg, Anders D., et al.
Publicado: (2016)

High-dose naloxone: Effects by late administration on pain and hyperalgesia following a human heat injury model. A randomized, double-blind, placebo-controlled, crossover trial with an enriched enrollment design
por: Springborg, Anders Deichmann, et al.
Publicado: (2020)

A Capsaicin (8%) Patch in the Treatment of Severe Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-Blind, Placebo-Controlled Trial
por: Bischoff, Joakim M., et al.
Publicado: (2014)

Secondary Hyperalgesia Phenotypes Exhibit Differences in Brain Activation during Noxious Stimulation
por: Asghar, Mohammad Sohail, et al.
Publicado: (2015)

Correction: Secondary Hyperalgesia Phenotypes Exhibit Differences in Brain Activation during Noxious Stimulation
por: Asghar, Mohammad Sohail, et al.
Publicado: (2015)

The Underestimated Significance of Conditioning in Placebo Hypoalgesia and Nocebo Hyperalgesia
por: Bräscher, Anne-Kathrin, et al.
Publicado: (2018)

Considering the Potential Benefits of Over-the-Counter Naloxone
por: Evoy, Kirk E, et al.
Publicado: (2021)

Reinstatement of memory representations for lifelike events over the course of a week
por: Oedekoven, Christiane S. H., et al.
Publicado: (2017)

Promises and perils of the FDA's over-the-counter naloxone reclassification
por: Zhu, David T., et al.
Publicado: (2023)

Oxydromus Grube, 1855 reinstated over Ophiodromus Sars, 1862 (Polychaeta, Hesionidae)
por: Villalobos-Guerrero, Tulio F., et al.
Publicado: (2012)

Sight restoration after congenital blindness does not reinstate alpha oscillatory activity in humans
por: Bottari, Davide, et al.
Publicado: (2016)

Healthy Volunteers Can Be Phenotyped Using Cutaneous Sensitization Pain Models
por: Werner, Mads U., et al.
Publicado: (2013)

Will converting naloxone to over‐the‐counter status increase pharmacy sales?
por: Murphy, Sean M., et al.
Publicado: (2019)

Reinstatement of "germinal epithelium" of the ovary
por: Nishida, Takashi, et al.
Publicado: (2006)

Gradual extinction reduces reinstatement
por: Shiban, Youssef, et al.
Publicado: (2015)

Reinstating the Novelty P3
por: Barry, Robert J., et al.
Publicado: (2016)

Reinstatement of Drs. Heath and May
Publicado: (1902)

Efficacy of naloxone in reducing postictal central respiratory dysfunction in patients with epilepsy: study protocol for a double-blind, randomized, placebo-controlled trial
por: Rheims, Sylvain, et al.
Publicado: (2016)

Classical conditioning without verbal suggestions elicits placebo analgesia and nocebo hyperalgesia
por: Bąbel, Przemysław, et al.
Publicado: (2017)

Placebo Analgesia, Nocebo Hyperalgesia, and the Cardiovascular System: A Qualitative Systematic Review
por: Daniali, Hojjat, et al.
Publicado: (2020)

Multichannel transcranial direct current stimulation over the left dorsolateral prefrontal cortex may modulate the induction of secondary hyperalgesia, a double-blinded cross-over study in healthy volunteers
por: Steyaert, Arnaud, et al.
Publicado: (2022)

An Improved Model of Heat-Induced Hyperalgesia—Repetitive Phasic Heat Pain Causing Primary Hyperalgesia to Heat and Secondary Hyperalgesia to Pinprick and Light Touch
por: Jürgens, Tim P., et al.
Publicado: (2014)

Point-of-sale Naloxone: Novel Community-based Research to Identify Naloxone Availability
por: Olives, Travis, et al.
Publicado: (2020)

Naloxone Audit
por: Venan, Paster
Publicado: (2023)

Degraded Land Restoration in Reinstating CH(4) Sink
por: Singh, Jay Shankar, et al.
Publicado: (2016)

Oscillatory Reinstatement Enhances Declarative Memory
por: Javadi, Amir-Homayoun, et al.
Publicado: (2017)

The Pathogenesis of Tuberculosis–The Koch Phenomenon Reinstated
por: Hunter, Robert L.
Publicado: (2020)

Contextual reinstatement affects semantic organization
por: Vaknin, Dana, et al.
Publicado: (2023)

Naloxone distribution and possession following a large‐scale naloxone programme
por: Madah‐Amiri, Desiree, et al.
Publicado: (2018)

Association of Naloxone Coprescription Laws With Naloxone Prescription Dispensing in the United States
por: Sohn, Minji, et al.
Publicado: (2019)

Distinct cortical systems reinstate the content and context of episodic memories
por: Kragel, James E., et al.
Publicado: (2021)

Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial
por: Kapitza, Christoph, et al.
Publicado: (2017)

Reconsidering the Usefulness of Adding Naloxone to Buprenorphine
por: Blazes, Christopher K., et al.
Publicado: (2020)

Reinstatement of extinguished fear by an unextinguished conditional stimulus
por: Halladay, Lindsay R., et al.
Publicado: (2012)

Reinstatement of the Chinese endemic species Styrax zhejiangensis
por: Ruan, Yu-Qing, et al.
Publicado: (2019)

Response to “Considering the Potential Benefits of Over-the-Counter Naloxone” by Evoy et al [Letter]
por: Fuehrlein, Brian
Publicado: (2021)

Sleep and Quality of Life Under Prolonged Release Oxycodone/Naloxone for Severe Restless Legs Syndrome: An Analysis of Secondary Efficacy Variables of a Double-Blind, Randomized, Placebo-Controlled Study with an Open-Label Extension
por: Oertel, Wolfgang H., et al.
Publicado: (2016)

The Area of Secondary Hyperalgesia following Heat Stimulation in Healthy Male Volunteers: Inter- and Intra-Individual Variance and Reproducibility
por: Hansen, Morten Sejer, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dhsrd84bq19nc84n8pepm1arlq