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REXO2 Is an Oligoribonuclease Active in Human Mitochondria

The Escherichia coli oligoribonuclease, ORN, has a 3′ to 5′ exonuclease activity specific for small oligomers that is essential for cell viability. The human homologue, REXO2, has hitherto been incompletely characterized, with only its in vitro ability to degrade small single-stranded RNA and DNA fr...

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Detalles Bibliográficos
Autores principales: Bruni, Francesco, Gramegna, Pasqua, Oliveira, Jorge M. A., Lightowlers, Robert N., Chrzanowska-Lightowlers, Zofia M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669425/
https://www.ncbi.nlm.nih.gov/pubmed/23741365
http://dx.doi.org/10.1371/journal.pone.0064670