Suprachoroidal delivery in a rabbit ex vivo eye model: influence of drug properties, regional differences in delivery, and comparison with intravitreal and intracameral routes

PURPOSE: First, to determine the influence of drug lipophilicity (using eight beta-blockers) and molecular weight (using 4 kDa and 40 kDa fluoroscein isothiocyanate [FITC]-dextrans) on suprachoroidal delivery to the posterior segment of the eye by using a rabbit ex vivo eye model. Second, to determi...

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Detalles Bibliográficos
Autores principales: Kadam, Rajendra S., Williams, Jason, Tyagi, Puneet, Edelhauser, Henry F., Kompella, Uday B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669536/
https://www.ncbi.nlm.nih.gov/pubmed/23734089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669536/
https://www.ncbi.nlm.nih.gov/pubmed/23734089

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