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Controlling DNA-end resection: a new task for CDKs

DNA double-strand breaks (DSBs) are repaired by two major pathways: homologous recombination (HR) and non-homologous end-joining (NHEJ). The choice between HR and NHEJ is highly regulated during the cell cycle. DNA-end resection, an evolutionarily conserved process that generates long stretches of s...

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Detalles Bibliográficos
Autores principales: Ferretti, Lorenza P., Lafranchi, Lorenzo, Sartori, Alessandro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669801/
https://www.ncbi.nlm.nih.gov/pubmed/23760669
http://dx.doi.org/10.3389/fgene.2013.00099