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Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression

Neuropeptide Y (NPY) has been implicated in depression, emotional processing and stress response. Part of this evidence originates from human single-nucleotide polymorphism (SNP) studies. In the present study, we report that a SNP in the rat Npy promoter (C/T; rs105431668) affects in vitro transcrip...

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Detalles Bibliográficos
Autores principales: Melas, P A, Lennartsson, A, Vakifahmetoglu-Norberg, H, Wei, Y, Åberg, E, Werme, M, Rogdaki, M, Mannervik, M, Wegener, G, Brené, S, Mathé, A A, Lavebratt, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669918/
https://www.ncbi.nlm.nih.gov/pubmed/23652932
http://dx.doi.org/10.1038/tp.2013.31