Isoforms of the neuronal glutamate transporter gene, SLC1A1/EAAC1, negatively modulate glutamate uptake: relevance to obsessive-compulsive disorder

The SLC1A1 gene, which encodes the neuronal glutamate transporter, EAAC1, has consistently been implicated in obsessive-compulsive disorder (OCD) in genetic studies. Moreover, neuroimaging, biochemical and clinical studies support a role for glutamatergic dysfunction in OCD. Although SLC1A1 is an ex...

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Detalles Bibliográficos
Autores principales: Porton, B, Greenberg, B D, Askland, K, Serra, L M, Gesmonde, J, Rudnick, G, Rasmussen, S A, Kao, H-T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669922/
https://www.ncbi.nlm.nih.gov/pubmed/23695234
http://dx.doi.org/10.1038/tp.2013.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669922/
https://www.ncbi.nlm.nih.gov/pubmed/23695234
http://dx.doi.org/10.1038/tp.2013.35

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