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A membrane penetrating peptide aptamer inhibits STAT3 function and suppresses the growth of STAT3 addicted tumor cells

Cancer cells are characterized by the aberrant activation of signaling pathways governing proliferation, survival, angiogenesis, migration and immune evasion. These processes are partially regulated by the transcription factor STAT3. This factor is inappropriately activated in diverse tumor types. S...

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Detalles Bibliográficos
Autores principales: Borghouts, Corina, Delis, Natalia, Brill, Boris, Weiss, Astrid, Mack, Laura, Lucks, Peter, Groner, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670134/
https://www.ncbi.nlm.nih.gov/pubmed/24058750
http://dx.doi.org/10.4161/jkst.18947