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Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells
LIF activates several intracellular signaling pathways including JAK-STAT, PI3K/AKT and MAPK pathways. LIF is an important cytokine for maintenance of pluripotency and self-renewal of mouse ES cells. The JAK-STAT signal plays a key role in maintenance of the pluripotency of ESCs. Recent evidence sho...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670240/ https://www.ncbi.nlm.nih.gov/pubmed/24058766 http://dx.doi.org/10.4161/jkst.21560 |