A rapid conformational rearrangement of STAT1 dimers is required for termination rather than for amplification of interferon-γ signaling

Sequence-specific binding of STAT1 (signal transducer and activator of transcription 1) transcription factor to palindromic promoter elements, termed γ-activated sites (GAS), and an extended spatial reorientation between two dimer configurations are key events in the interferon signaling pathway. Al...

Descripción completa

Detalles Bibliográficos
Autores principales: Staab, Julia, Herrmann-Lingen, Christoph, Meyer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670273/
https://www.ncbi.nlm.nih.gov/pubmed/24058797
http://dx.doi.org/10.4161/jkst.23576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670273/
https://www.ncbi.nlm.nih.gov/pubmed/24058797
http://dx.doi.org/10.4161/jkst.23576

Ejemplares similares