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Therapeutic targeting of STAT pathways in CNS autoimmune diseases

Signal transducers and activators of transcription (STATs) transduce extracellular signals that regulate the initiation, duration and intensity of immune responses. However, unbridled activation of STATs by pro-inflammatory cytokines or growth factors contributes to pathogenic autoimmunity. In this...

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Detalles Bibliográficos
Autores principales: Egwuagu, Charles E., Larkin, III, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670276/
https://www.ncbi.nlm.nih.gov/pubmed/24058800
http://dx.doi.org/10.4161/jkst.24134