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Targeting STATs for cancer therapy: “Undruggable” no more
We are in the midst of an exciting transition in the treatment of cancers, from the empirically developed non-specifically cytotoxic drugs to the era of rationally derived molecularly targeted therapies. Over the past 15 years, our understanding of the mutations that drive cancer pathogenesis has gr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670283/ https://www.ncbi.nlm.nih.gov/pubmed/24058782 http://dx.doi.org/10.4161/jkst.22528 |