Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation

Most attempts to develop inhibitors of STAT transcription factors target either activating phosphorylation of tyrosine residue or SH2 domains. However, all six domains of STATs are highly conserved between the species and play important roles in the function of this family of transcription factors....

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Detalles Bibliográficos
Autores principales: Timofeeva, Olga A., Tarasova, Nadya I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670285/
https://www.ncbi.nlm.nih.gov/pubmed/24058784
http://dx.doi.org/10.4161/jkst.22313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670285/
https://www.ncbi.nlm.nih.gov/pubmed/24058784
http://dx.doi.org/10.4161/jkst.22313

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