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Screening approaches to generating STAT inhibitors: Allowing the hits to identify the targets
STAT transcription factors are regulators of critical cellular processes such as proliferation, survival, and self-renewal. While the activity of these proteins is tightly regulated under physiological conditions, they can become constitutively activated in a broad range of human cancers. This inapp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670287/ https://www.ncbi.nlm.nih.gov/pubmed/24058786 http://dx.doi.org/10.4161/jkst.22662 |