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STAT signaling in the pathogenesis and treatment of myeloid malignancies

STAT transcription factors play a critical role in mediating the effects of cytokines on myeloid cells. As STAT target genes control key processes such as survival, proliferation and self-renewal, it is not surprising that constitutive activation of STATs, particularly STAT3 and STAT5, are common ev...

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Detalles Bibliográficos
Autores principales: Bar-Natan, Michal, Nelson, Erik A., Xiang, Michael, Frank, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670294/
https://www.ncbi.nlm.nih.gov/pubmed/24058751
http://dx.doi.org/10.4161/jkst.20006