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STAT1 and STAT3 in tumorigenesis: A matter of balance

The transcription factors STAT1 and STAT3 appear to play opposite roles in tumorigenesis. While STAT3 promotes cell survival/proliferation, motility and immune tolerance and is considered as an oncogene, STAT1 mostly triggers anti-proliferative and pro-apoptotic responses while enhancing anti-tumor...

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Detalles Bibliográficos
Autores principales: Avalle, Lidia, Pensa, Sara, Regis, Gabriella, Novelli, Francesco, Poli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670295/
https://www.ncbi.nlm.nih.gov/pubmed/24058752
http://dx.doi.org/10.4161/jkst.20045