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Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers

BACKGROUND: BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its frequency in breast cancer is not known. Assays to establish BRCAness would be extremely valuable for the clinical management of these tumours....

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Detalles Bibliográficos
Autores principales: Lips, E H, Mulder, L, Oonk, A, van der Kolk, L E, Hogervorst, F B L, Imholz, A L T, Wesseling, J, Rodenhuis, S, Nederlof, P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670471/
https://www.ncbi.nlm.nih.gov/pubmed/23558900
http://dx.doi.org/10.1038/bjc.2013.144