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Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells

BACKGROUND: Wnt-signalling has an important role in renal cancer and it is modulated by genistein in other cancers. Recently, microRNAs (miRNAs) have emerged as new regulators of gene expression. Thus, we focused on miRNAs to examine the regulatory mechanism of genistein on the Wnt-signalling pathwa...

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Detalles Bibliográficos
Autores principales: Hirata, H, Ueno, K, Nakajima, K, Tabatabai, Z L, Hinoda, Y, Ishii, N, Dahiya, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670482/
https://www.ncbi.nlm.nih.gov/pubmed/23591200
http://dx.doi.org/10.1038/bjc.2013.173