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Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2-positive metastatic breast cancer
INTRODUCTION: Neratinib is a potent irreversible pan-ErbB tyrosine kinase inhibitor that has demonstrated antitumour activity and an acceptable safety profile in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer and other solid tumours. METHODS: This was a phase I/I...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670493/ https://www.ncbi.nlm.nih.gov/pubmed/23632474 http://dx.doi.org/10.1038/bjc.2013.178 |