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Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2-positive metastatic breast cancer

INTRODUCTION: Neratinib is a potent irreversible pan-ErbB tyrosine kinase inhibitor that has demonstrated antitumour activity and an acceptable safety profile in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer and other solid tumours. METHODS: This was a phase I/I...

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Detalles Bibliográficos
Autores principales:	Chow, L W-C, Xu, B, Gupta, S, Freyman, A, Zhao, Y, Abbas, R, Vo Van, M-L, Bondarenko, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670493/ https://www.ncbi.nlm.nih.gov/pubmed/23632474 http://dx.doi.org/10.1038/bjc.2013.178

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