The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer

BACKGROUND: Mutations in KRAS, BRAF, PIK3CA and PTEN expression have been in focus to predict the effect of epidermal growth factor receptor-blocking therapy in colorectal cancer (CRC). Here, information on these four aberrations was collected and combined to a Quadruple index and used to evaluate t...

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Detalles Bibliográficos
Autores principales: Eklöf, V, Wikberg, M L, Edin, S, Dahlin, A M, Jonsson, B-A, Öberg, Å, Rutegård, J, Palmqvist, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670497/
https://www.ncbi.nlm.nih.gov/pubmed/23660947
http://dx.doi.org/10.1038/bjc.2013.212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670497/
https://www.ncbi.nlm.nih.gov/pubmed/23660947
http://dx.doi.org/10.1038/bjc.2013.212

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