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Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKKβ Activity and JNK Phosphorylation

The key role of T cells has been elaborated in mediating immune responses and pathogenesis of human inflammatory and autoimmune conditions. In the current study the effect of shikonin, a compound isolated from a medicinal plant, on inhibition of T-cell activation was firstly examined by using primar...

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Detalles Bibliográficos
Autores principales: Li, Ting, Yan, Fenggen, Wang, Rui, Zhou, Hua, Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670545/
https://www.ncbi.nlm.nih.gov/pubmed/23762128
http://dx.doi.org/10.1155/2013/379536