Effects of Sample Size on Differential Gene Expression, Rank Order and Prediction Accuracy of a Gene Signature

Top differentially expressed gene lists are often inconsistent between studies and it has been suggested that small sample sizes contribute to lack of reproducibility and poor prediction accuracy in discriminative models. We considered sex differences (69♂, 65♀) in 134 human skeletal muscle biopsies...

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Detalles Bibliográficos
Autores principales: Stretch, Cynthia, Khan, Sheehan, Asgarian, Nasimeh, Eisner, Roman, Vaisipour, Saman, Damaraju, Sambasivarao, Graham, Kathryn, Bathe, Oliver F., Steed, Helen, Greiner, Russell, Baracos, Vickie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670871/
https://www.ncbi.nlm.nih.gov/pubmed/23755224
http://dx.doi.org/10.1371/journal.pone.0065380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670871/
https://www.ncbi.nlm.nih.gov/pubmed/23755224
http://dx.doi.org/10.1371/journal.pone.0065380

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