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Treponema denticola Major Outer Sheath Protein Impairs the Cellular Phosphoinositide Balance That Regulates Neutrophil Chemotaxis

The major outer sheath protein (Msp) of Treponema denticola inhibits neutrophil polarization and directed chemotaxis together with actin dynamics in vitro in response to the chemoattractant N-formyl-methionine-leucine-phenylanine (fMLP). Msp disorients chemotaxis through inhibition of a Rac1-depende...

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Detalles Bibliográficos
Autores principales: Visser, Michelle B., Sun, Chun-Xiang, Koh, Adeline, Ellen, Richard P., Glogauer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670873/
https://www.ncbi.nlm.nih.gov/pubmed/23755300
http://dx.doi.org/10.1371/journal.pone.0066209