A New Functional Site W115 in CdtA Is Critical for Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin

Aggregatibacter actinomycetemcomitans, a specific pathogen of localized aggressive periodontitis, produces a cytolethal distending toxin (CDT) that arrests eukaryotic cells irreversibly in G0/G1 or G2/M phase of the cell cycle. Although structural studies show that the aromatic patch region of CdtA...

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Detalles Bibliográficos
Autores principales: Li, Lu, Ding, Cheng, Duan, Jun-lan, Yang, Mi-fang, Sun, Ying, Wang, Xiao-qian, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670888/
https://www.ncbi.nlm.nih.gov/pubmed/23755273
http://dx.doi.org/10.1371/journal.pone.0065729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670888/
https://www.ncbi.nlm.nih.gov/pubmed/23755273
http://dx.doi.org/10.1371/journal.pone.0065729

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