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Mechanisms That Enhance Sustainability of p53 Pulses

The tumor suppressor p53 protein shows various dynamic responses depending on the types and extent of cellular stresses. In particular, in response to DNA damage induced by γ-irradiation, cells generate a series of p53 pulses. Recent research has shown the importance of sustaining repeated p53 pulse...

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Detalles Bibliográficos
Autores principales: Kim, Jae Kyoung, Jackson, Trachette L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670918/
https://www.ncbi.nlm.nih.gov/pubmed/23755198
http://dx.doi.org/10.1371/journal.pone.0065242