Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain

AIMS/HYPOTHESIS: We analysed the genomic organisation of miR-153, a microRNA embedded in genes that encode two of the major type 1 diabetes autoantigens, islet-associated protein (IA)-2 and IA-2β. We also identified miR-153 target genes that correlated with IA-2β localisation and function. METHODS:...

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Detalles Bibliográficos
Autores principales: Mandemakers, W., Abuhatzira, L., Xu, H., Caromile, L. A., Hébert, S. S., Snellinx, A., Morais, V. A., Matta, S., Cai, T., Notkins, A. L., De Strooper, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671108/
https://www.ncbi.nlm.nih.gov/pubmed/23595248
http://dx.doi.org/10.1007/s00125-013-2901-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671108/
https://www.ncbi.nlm.nih.gov/pubmed/23595248
http://dx.doi.org/10.1007/s00125-013-2901-5

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