Cargando…

Functional differences between aggregated and dispersed insulin-producing cells

AIMS/HYPOTHESIS: Beta cells situated in the islet of Langerhans respond more vigorously to glucose than do dissociated beta cells. Mechanisms for this discrepancy were studied by comparing insulin-producing MIN6 cells aggregated into pseudoislets with MIN6 monolayer cells and mouse and human islets....

Descripción completa

Detalles Bibliográficos
Autores principales: Chowdhury, A., Dyachok, O., Tengholm, A., Sandler, S., Bergsten, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671110/
https://www.ncbi.nlm.nih.gov/pubmed/23604550
http://dx.doi.org/10.1007/s00125-013-2903-3