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Functional differences between aggregated and dispersed insulin-producing cells

AIMS/HYPOTHESIS: Beta cells situated in the islet of Langerhans respond more vigorously to glucose than do dissociated beta cells. Mechanisms for this discrepancy were studied by comparing insulin-producing MIN6 cells aggregated into pseudoislets with MIN6 monolayer cells and mouse and human islets....

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Detalles Bibliográficos
Autores principales:	Chowdhury, A., Dyachok, O., Tengholm, A., Sandler, S., Bergsten, P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671110/ https://www.ncbi.nlm.nih.gov/pubmed/23604550 http://dx.doi.org/10.1007/s00125-013-2903-3

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