Phase-defined complete sequencing of the HLA genes by next-generation sequencing

BACKGROUND: The human leukocyte antigen (HLA) region, the 3.8-Mb segment of the human genome at 6p21, has been associated with more than 100 different diseases, mostly autoimmune diseases. Due to the complex nature of HLA genes, there are difficulties in elucidating complete HLA gene sequences espec...

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Detalles Bibliográficos
Autores principales: Hosomichi, Kazuyoshi, Jinam, Timothy A, Mitsunaga, Shigeki, Nakaoka, Hirofumi, Inoue, Ituro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671147/
https://www.ncbi.nlm.nih.gov/pubmed/23714642
http://dx.doi.org/10.1186/1471-2164-14-355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671147/
https://www.ncbi.nlm.nih.gov/pubmed/23714642
http://dx.doi.org/10.1186/1471-2164-14-355

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