SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia

Global increases in small ubiquitin-like modifier (SUMO)-2/3 conjugation are a neuroprotective response to severe stress but the mechanisms and specific target proteins that determine cell survival have not been identified. Here, we demonstrate that the SUMO-2/3-specific protease SENP3 is degraded d...

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Detalles Bibliográficos
Autores principales: Guo, Chun, Hildick, Keri L, Luo, Jia, Dearden, Laura, Wilkinson, Kevin A, Henley, Jeremy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671254/
https://www.ncbi.nlm.nih.gov/pubmed/23524851
http://dx.doi.org/10.1038/emboj.2013.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671254/
https://www.ncbi.nlm.nih.gov/pubmed/23524851
http://dx.doi.org/10.1038/emboj.2013.65

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