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SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
Global increases in small ubiquitin-like modifier (SUMO)-2/3 conjugation are a neuroprotective response to severe stress but the mechanisms and specific target proteins that determine cell survival have not been identified. Here, we demonstrate that the SUMO-2/3-specific protease SENP3 is degraded d...
Autores principales: | Guo, Chun, Hildick, Keri L, Luo, Jia, Dearden, Laura, Wilkinson, Kevin A, Henley, Jeremy M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671254/ https://www.ncbi.nlm.nih.gov/pubmed/23524851 http://dx.doi.org/10.1038/emboj.2013.65 |
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