Systemic Delivery of Tyrosine-Mutant AAV Vectors Results in Robust Transduction of Neurons in Adult Mice

Recombinant adeno-associated virus (AAV) vectors are powerful tools for both basic neuroscience experiments and clinical gene therapies for neurological diseases. Intravascularly administered self-complementary AAV9 vectors can cross the blood-brain barrier. However, AAV9 vectors are of limited usef...

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Detalles Bibliográficos
Autores principales: Iida, Asako, Takino, Naomi, Miyauchi, Hitomi, Shimazaki, Kuniko, Muramatsu, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671507/
https://www.ncbi.nlm.nih.gov/pubmed/23762870
http://dx.doi.org/10.1155/2013/974819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671507/
https://www.ncbi.nlm.nih.gov/pubmed/23762870
http://dx.doi.org/10.1155/2013/974819

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