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Systemic Delivery of Tyrosine-Mutant AAV Vectors Results in Robust Transduction of Neurons in Adult Mice

Recombinant adeno-associated virus (AAV) vectors are powerful tools for both basic neuroscience experiments and clinical gene therapies for neurological diseases. Intravascularly administered self-complementary AAV9 vectors can cross the blood-brain barrier. However, AAV9 vectors are of limited usef...

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Detalles Bibliográficos
Autores principales:	Iida, Asako, Takino, Naomi, Miyauchi, Hitomi, Shimazaki, Kuniko, Muramatsu, Shin-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671507/ https://www.ncbi.nlm.nih.gov/pubmed/23762870 http://dx.doi.org/10.1155/2013/974819

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