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Neuroprotective Function of DJ-1 in Parkinson's Disease

Parkinson's disease (PD) is caused by dopaminergic neuronal death in the substantia nigra, resulting in a reduced level of dopamine in the striatum. Oxidative stress and mitochondrial dysfunction are thought to be major causes of neurodegeneration in PD. Although genetic and environmental facto...

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Detalles Bibliográficos
Autores principales: Ariga, Hiroyoshi, Takahashi-Niki, Kazuko, Kato, Izumi, Maita, Hiroshi, Niki, Takeshi, Iguchi-Ariga, Sanae M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671546/
https://www.ncbi.nlm.nih.gov/pubmed/23766857
http://dx.doi.org/10.1155/2013/683920